Frontiers of hypoxia research: acute mountain sickness

Acute Mountain Sickness Symptoms Depend on Normobaric versus Hypobaric Hypoxia

Acute mountain sickness (AMS), characterized by headache, nausea, fatigue, and dizziness when unacclimatized individuals rapidly ascend to high altitude, is exacerbated by exercise and can be disabling. Although AMS is observed in both normobaric (NH) and hypobaric hypoxia (HH), recent evidence suggests that NH and HH produce different physiological responses. We evaluated whether AMS symptoms ...

Severe acute mountain sickness.

The experiences of acute mountain sickness (AMS) as it has presented to a physician working in a general hospital at 1370 m in Kathmandu, nepal, are described. The features of 39 cases are analysed. It is suggested that AMS should be classified into benign and malignant forms.

Acute mountain sickness.

Acute mountain sickness (AMS) is a clinical syndrome occurring in otherwise healthy normal individuals who ascend rapidly to high altitude. Symptoms develop over a period ofa few hours or days. The usual symptoms include headache, anorexia, nausea, vomiting, lethargy, unsteadiness of gait, undue dyspnoea on moderate exertion and interrupted sleep. AMS is unrelated to physical fitness, sex or ag...

Acute mountain sickness.

Frontiers of hypoxia research

Acute mountain sickness Many hundreds of studies of AMS over the past two centuries have examined the contributions of ventilation, pulmonary gas exchange and fluid balance to the pathophysiology of AMS. Unfortunately, the traditional paradigm that invoked these peripheral responses to acute hypobaric hypoxia to explain AMS failed to substantially advance our understanding. Therefore, this revi...